MTOR

[Cell Reports] Liver cells with disordered tyrosine catabolism, as exemplified by the suppression of a tyrosine catabolic enzyme 4-hydroxyphenylpyruvate dioxygenase (HPD), displayed augmented tumorigenic and proliferative potentials.

[Scientific Reports] The authors explored expression patterns and prognostic value of secretory carrier-associated membrane proteins (SCAMPs) and network analysis of SCAMPs-related signaling pathways in acute myeloid leukemia using Oncomine, GEPIA, cBioPortal, LinkedOmics, DAVID and Metascape databases.

[Journal of Physiology and Biochemistry] The proliferative, migratory, and angiogenic abilities of HUVECs were enhanced after exposure to exosomes derived from HCC cells by transmitting SNHG16. SNHG16 was validated to promote the biological function of HUVECs directly.

[FASEB Journal] Researchers found that specific inhibition of MyD88 reduces the activation of canonical nuclear factor-kappa pathway and expression of receptors for inflammatory cytokines in denervated muscle.

[Cardiovascular Toxicology] To investigate the role of CAIII in the apoptosis of myocytes under hypoxic conditions and facilitate the strategy for treating hypoxia-induced damage, in vitro experiments in H9c2 were employed.

[eLife] The authors identified 6-phosphogluoconate dehydrogenase as an androgen-regulated gene that was upregulated in prostate cancer.