Tag results:
NSCLC
Pulmonary Cell News
LncRNA HOXC-AS3 Promotes Non-Small-Cell Lung Cancer Growth and Metastasis through Upregulation of YBX1
[Cell Death & Disease] The authors explored the molecular mechanisms underlying NSCLC development, focusing on the HOXC-AS3/YBX1/HOXC8 axis.
Pulmonary Cell News
Targeting Nicotinamide N-Methyltransferase Overcomes Resistance to EGFR-TKI in Non-Small Cell Lung Cancer Cells
[Cell Death Discovery] Using iTRAQ-based quantitative proteomics analysis, we identified that nicotinamide N-methyltransferase was significantly increased in epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)-resistant NSCLC cells.
Pulmonary Cell News
Targeting lncRNAs in Programmed Cell Death as a Therapeutic Strategy for Non-Small Cell Lung Cancer
[Cell Death Discovery] The authors focus on the function of lncRNAs in programmed cell death (PCD) of NSCLC and summarize the therapeutic role of targeting lncRNAs in PCD for NSCLC treatment
Human Immunology News
Genprex Announces the Opening for Enrollment of its Phase I/II Acclaim-2 Clinical Trial of REQORSA™ Immunogene Therapy in Combination With Keytruda® to Treat Non-Small...
[Genprex, Inc.] Genprex, Inc. announced the opening for patient enrollment of its Acclaim-2 clinical trial, an open-label, multi-center Phase I/II clinical trial evaluating the Company’s lead drug candidate, REQORSA™ Immunogene Therapy, in combination with Keytruda® in patients with late-stage non-small cell lung cancer whose disease progressed after treatment with Keytruda.
Pulmonary Cell News
MicroRNA-631 Deriving from Bone Marrow Mesenchymal Stem Cell Exosomes Facilitates the Malignant Behavior of Non-small Cell Lung Cancer via Modulating the E2F Family of...
[Bioengineered] Researchers explored the potential mechanism of exosome-derived miR-631 targeting and regulating E2F family of transcription factor 2 to repress the malignant behavior of NSCLC cells.
Pulmonary Cell News
The Expression of PD-1 Ligand 1 on Macrophages and Its Clinical Impacts and Mechanisms in Lung Adenocarcinoma
[Cancer Immunology Immunotherapy] In an in vitro study using lung cancer cell lines and human monocyte-derived macrophages, the conditioned medium from cancer cells was found to up-regulate programmed cell death-1 ligand 1 expression on macrophages via STAT3 activation.