NSCLC

[Bioengineered] Quercitrin prohibited the cell viability and clone-formation of lung adenocarcinoma cells in vitro.

[Bioengineered] Scientists suggested that circ-UBE2D2 promoted the proliferation, migration and invasion but restrained apoptosis of lung cancer cells by regulating miR-376a-3p/eukaryotic translation initiation factor 4γ2 axis.

[Environmental Science and Pollution Research] Investigators formulated berberine-loaded liquid crystalline nanoparticles and investigated their in vitro antiproliferative and antimigratory activity in a human lung epithelial cancer cell line.

[Zai Lab Limited] Zai Lab Limited announced that the Center for Drug Evaluation of the National Medical Products Administration granted Breakthrough Therapy Designation for investigational repotrectinib for the treatment of patients with ROS1-positive metastatic NSCLC who have not been treated with a ROS1 tyrosine kinase inhibitor.

[Cancer Letters] The authors investigated the role of the tumor stem cell marker DCLK1 in epithelial growth factor receptor-tyrosine kinase inhibitor resistance of lung adenocarcinoma.

[Thoracic Cancer] Investigators revealed that high serum IL-35 expression was associated with NSCLC cachexia and skeletal muscle atrophy.