Tag results:
Nanog
Cancer Stem Cell News
Increased Expression of PD-L1 in Endometrial Cancer Stem-Like Cells Is Regulated by Hypoxia
[Frontiers in Bioscience-Landmark] Using flow cytometry and western blot assays, the authors have demonstrated that programmed cell death ligand 1 expression is higher in endometrial cancer stem-like cell derived from endometrial cancer than in nonstem-like cancer cells.
Cancer Stem Cell News
MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation
[Stem Cells International] Researchers explored whether Mesenchymal stem cell- (MSC-) derived extracellular vesicles-delivered lipocalin-type prostaglandin D2 synthase (L-PGDS) could inhibit gastric cancer progression.
Cancer Stem Cell News
Deregulation of the CD44-NANOG-MDR1 Associated Chemoresistance Pathways of Breast Cancer Stem Cells Potentiates the Anti-cancer Effect of Kaempferol in Synergism with Verapamil
[Toxicology and Applied Pharmacology] Researchers used Kaempferol in combination with Verapamil, in multiple assays to determine if there was an inhibitory effect on breast cancer stem cells.
ESC & iPSC News
ZFP207 Sustains Pluripotency by Coordinating OCT4 Stability, Alternative Splicing and RNA Export
[EMBO Reports] The authors employed multiple functional analyses to characterize the role of Zinc Finger Protein 207 (ZFP207) in mouse ESCs.
Cancer Stem Cell News
MACC1 Regulates the AKT/STAT3 Signaling Pathway to Induce Migration, Invasion, Cancer Stemness, and Suppress Apoptosis in Cervical Cancer Cells
[Bioengineered] Researchers verified that treatment with the STAT3 activator had significant reversal effects on the malignant behaviors of cervical cancer (CC) cells and CC stemness.
ESC & iPSC News
Differential Repression of Otx2 Underlies the Capacity of NANOG and ESRRB to Induce Germline Entry
[Stem Cell Reports] Investigators showed that NANOG mediated Otx2 downregulation in the absence of cytokines and that this was essential for primordial germ cell-like cells induction by NANOG.