Nanog

[Journal of Translational Medicine] The expression of miR-3065-3p in colorectal cancer and the association of miR-3065-3p expression with prognosis of patients with colorectal cancer were analyzed using TCGA dataset or clinical cases.

[Biology Open] Activation of activin A signaling stimulated NANOG expression during self-renewal of bovine ESC but suppressed cells expressing pluripotency markers in the blastocyst and increased cells expressing CDX2.

[Cell Death Discovery] The authors found that the stemness characteristics of lung cancer cells were significantly enhanced by the overexpression of non-muscle myosin heavy chain 9 (MYH9), and the knockout of MYH9 had the opposite effects.

[Scientific Reports] Researchers used miR-27b-inducible human iPSCs (hiPSCs) to investigate the roles of miR-27b in the undifferentiated and early-differentiated stages. In undifferentiated hiPSCs, miR-27b suppressed the expression of pluripotency markers and cell proliferation.

[Life Science Alliance] The authors used Resf1 knockout cell lines to determine the requirements of RESF1 for ESC self-renewal and for in vitro specification of ESCs into primordial germ cell-like cells

[Cellular Oncology] Cell line-derived spheroids, ex vivo intestinal organoid cultures and induced-pluripotent stem cells were used to investigate the role of atypical cyclin P in stemness.