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Nos2

Chemical Inducer of Regucalcin Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Pancreatic MIN6 β-Cells and RAW264.7 Macrophages

[Febs Open Bio] Scientists reported that derrisfolin A induced the expression of endogenous regucalcin protein in both pancreatic MIN6 β-cells and RAW264.7 macrophages.

Disrupted NOS2 Metabolism Drives Myoblast Response to Wasting-Associated Cytokines

[Experimental Cell Research] Researchers combined gene expression and non-targeted metabolomic profiling of myoblasts exposed to wasting conditions to derive a more complete picture of the myoblast response to wasting factors.

ITLN1 Inhibits Tumor Neovascularization and Myeloid Derived Suppressor Cells Accumulation in Colorectal Carcinoma

[Oncogene] Researchers explored the inhibitory role of ITLN1 in the tumor-permissive microenvironment that existed during the first occurrence and subsequent development of colorectal carcinoma.

Comparison of Mesenchymal Stromal Cells from Peritoneal Dialysis Effluent with Those from Umbilical Cords: Characteristics and Therapeutic Effects on Chronic Peritoneal Dialysis in Uremic...

[Stem Cell Research & Therapy] Researchers compared the cytoprotection between peritoneal dialysis (PD) effluent-derived MSCs and umbilical cord-derived MSCs in the treatment of both peritoneal membrane and kidney injury in uremic rats with chronic PD.

Neutrophil Oxidative Stress Mediates Obesity-Associated Vascular Dysfunction and Metastatic Transmigration

[Nature Cancer] Scientists showed that obesity led to neutrophil-dependent impairment of vascular integrity through loss of endothelial adhesions, enabling cancer cell extravasation into the lung.

Mechanistic and Therapeutic Distinctions between Cardiosphere-Derived Cell and Mesenchymal Stem Cell Extracellular Vesicle Non-Coding RNA

[Scientific Reports] Investigators compared extracellular vesicles derived from multiple human mesenchymal stem cell and cardiosphere-derived cell donors using diverse in vitro and in vivo assays.

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