Xeno-Free Condition Enhances Therapeutic Functions of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells against Experimental Colitis by Upregulated Indoleamine 2,3-Dioxygenase Activity

Researcchers extensively compared the physiological functions of human Wharton’s jelly-derived mesenchymal stem cells in a xeno-free medium and a medium containing 10% fetal bovine serum.
[Journal of Clinical Medicine]
Kang, J. Y., Oh, M.-K., Joo, H., Park, H. S., Chae, D.-H., Kim, J., Lee, H.-R., Oh, I.-H., & Yu, K.-R. (2020). Xeno-Free Condition Enhances Therapeutic Functions of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells against Experimental Colitis by Upregulated Indoleamine 2,3-Dioxygenase Activity. Journal of Clinical Medicine, 9(9), 2913. https://doi.org/10.3390/jcm9092913 Cite
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IL-17F Induces Inflammation, Dysfunction and Cell Death in Mouse Islets

IL-17F possessed similar pathogenic activities to IL-17A in mouse β-cell lines and islets and was likely to be a type 17 associated pathogenic factor in type 1 diabetes.
[Scientific Reports]
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