Oct4

[EMBO Reports] The authors employed multiple functional analyses to characterize the role of Zinc Finger Protein 207 (ZFP207) in mouse ESCs.

[Cell Biology International] HPV16 E6 silence or overexpression were carried out to evaluate the possible mechanisms of HPV16 E6 function in cervical cancer cells with different HPV16 E6 expression background.

[Bioengineered] Researchers verified that treatment with the STAT3 activator had significant reversal effects on the malignant behaviors of cervical cancer (CC) cells and CC stemness.

[Stem Cells International] Scientists discovered that p57Kip2 (p57), a cyclin-dependent kinase inhibitor canonically inhibiting cell proliferation, played a role in suppressing the pluripotency state of mouse ESCs.

[Nature Communications] Using two independent TNBC models, the authors reported a discrete subpopulation of highly metastatic SOX2/OCT4+ cells within primary tumors that exhibitrf elevated intracellular copper levels and a marked sensitivity to tetrathiomolybdate.

[Military Medical Research] Researchers evaluated the antitumor activities of LR004-VC-MMAE against epidermal growth factor receptor (EGFR)-positive TNBC and further studied its possible mechanism of antitumor action.