PBMCs

[Proteomics] The study of molecular content of peripheral blood mononuclear cells can provide better understanding of immune processes giving the possibility of monitoring the health conditions of the host organism.

[American Journal of Respiratory and Critical Care Medicine] Researchers characterized the functional SARS-CoV-2 T cell responses in severe versus recovered, mild COVID-19 patients to determine whether differences were detectable.

[Nature Biotechnology] The authors described an implantable Multifunctional Alginate Scaffold for T Cell Engineering and Release that streamlined in vivo CAR-T cell manufacturing and reduced processing time to a single day.

[PLoS One] Scientists conducted a single center observational cohort study of patients diagnosed with intermittent claudication. Blood and urine samples were collected at rest and following a standardized treadmill exercise protocol.

[JCI Insight] Researchers showed that myeloproliferative neoplasm (MPN)-blast phase (BP) initiating cells originated from not only phenotypically identified hematopoietic stem cells but also lymphoid-myeloid progenitor cells which were each characterized by differences in MPN-BP initiating activity and self-renewal capacity.

[Cell] Scientists identified a family of Enterococcus pore-forming toxins in E. faecalis, E. faecium, and E. hirae strains isolated across the globe.