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PBMCs

HLA-A*11:01-Restricted CD8+ T Cell Immunity against Influenza A and Influenza B Viruses in Indigenous and Non-Indigenous People

[PLoS Pathogens] Investigators embarked on an epitope discovery study to define a CD8+ T cell landscape for HLA-A*11:01-expressing Indigenous and non-Indigenous Australian people.

Single-Cell Isoform Analysis in Human Immune Cells

[Genome Biology] The authors used R2C2 to sequence and demultiplex 12 million full-length cDNA molecules generated by the 10X Genomics platform from ~3000 peripheral blood mononuclear cells.

Development of a Skin- and Neuro-Attenuated Live Vaccine for Varicella

[Nature Communications] A rationally design a live-attenuated varicella vaccine candidate, v7D, showed immunogenicity comparable to vOka both in vitro and in multiple small animal species.

Weekly Treatment with SAMiRNA Targeting the Androgen Receptor Ameliorates Androgenetic Alopecia

[Scientific Reports] SAMiRNA-AR68 could be efficiently delivered to human follicle dermal papilla cells and hair follicles, and this treatment decreased the androgen receptor mRNA and protein levels.

Gene Therapy of Prostate Cancer Using Liposomes Containing Perforin Expression Vector Driven by the Promoter of Prostate-Specific Antigen Gene

[Scientific Reports] The authors investigated the therapeutic potential of liposomes containing perforin expression vector driven by the promotor of prostate-specific antigen.

Lung-Resident Memory B Cells Established after Pulmonary Influenza Infection Display Distinct Transcriptional and Phenotypic Profiles

[Science Immunology] Scientists characterized tissue-resident memory B cells that were stably maintained in the lungs of mice after pulmonary influenza infection.

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