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PDAC cells

Circ_0072008, an Oncogene in Pancreatic Ductal Adenocarcinoma, Contributes to Tumour Cell Malignant Progression and Glycolysis by Regulating miR-545-3p/SLC7A11 Axis

[Autoimmunity] Expression of circ_0072088, microRNA (miR)-545-3p and solute carrier family 7 member 11 (SLC7A11) was detected by real-time quantitative PCR and western blotting.

Circ_0072008, an Oncogene in Pancreatic Ductal Adenocarcinoma, Contributes to Tumour Cell Malignant Progression and Glycolysis by Regulating miR-545-3p/SLC7A11 Axis

[Autoimmunity] Expression of circ_0072088, microRNA (miR)-545-3p and solute carrier family 7 member 11 (SLC7A11) was detected by real-time quantitative PCR and western blotting.

The Significance of ErbB2/3 in the Conversion of Induced Pluripotent Stem Cells into Cancer Stem Cells

[Scientific Reports] Scientists analyzed the transcriptome of cancer stem cells, which were converted from iPSCs with conditioned medium from pancreatic ductal adenocarcinoma cells.

Transforming Growth Factor-β Challenge Alters the N-, O-, and Glycosphingolipid Glycomes in PaTu-S Pancreatic Adenocarcinoma Cells

[Journal of Biological Chemistry] Researchers examined differences in N-glycans, O-glycans, and glycosphingolipid glycans in PaTu-8955S (PaTu-S) cells upon TGF-β stimulation.

Synthetic Adiponectin-Receptor Agonist, AdipoRon, Induces Glycolytic Dependence in Pancreatic Cancer Cells

[Cell Death & Disease] Treatment of PDAC cells with AdipoRon led to mitochondrial uncoupling and loss of ATP production. Concomitantly, AdipoRon-treated cells increased glucose uptake and utilization.

Fungal Mycobiome Drives IL-33 Secretion and Type 2 Immunity in Pancreatic Cancer

[Cancer Cell] The authors showed that oncogenic KrasG12D increased IL-33 expression in PDAC cells, which recruited and activated TH2 and innate lymphoid cells 2 cells.

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