PDGF

[Cell Communication and Signaling] Researchers studied the functions of umbilical cord MSCs-released extracellular vesicles and their implicated molecules in mesangial proliferative glomerulonephritis.

[Stem Cell Research & Therapy] Investigators examined whether by phosphatase regenerating liver-1, overexpressed placental-derived-MSCs, could maximize the angiogenic effects in ovarian tissues injured of a rat model with partial ovariectomy.

[Journal of Ethnopharmacology] Shuxuetong injection promoted angiogenesis and improved function recovery in hindlimb ischemia mice by regulation of VEGF-A/platelet-derived growth factor.

[American Journal of Respiratory Cell and Molecular Biology] A long non-coding RNA attenuated by platelet-derived growth factor BB was identified and its functional roles were investigated in vitro and in vivo.

[Signal Transduction and Targeted Therapy] EPHA2 might contribute to platelet-derived growth subunit A (PDGFA) signaling transduction in combination with platelet-derived growth receptor α (PDGFRA) and mediate the resistance of glioblastoma cells to PDGFRA inhibitor.

[Cell Death & Disease] Knockdown of myocardin (MYOCD) in human aortic VSMCs triggered autophagy and diminished the expression of SMC contractile proteins. Inhibition of autophagy in MYOCD-knockdown cells restored the expression of contractile proteins.