SHH

[Development] Researchers demonstrated that selective deletion of stromal androgen-receptor expression in prepubescent Shh responsive Gli1-expressing cells significantly impeded pubertal prostate epithelial growth and development.

[Stem Cell Research & Therapy] Scientists highlight the potential mechanisms underlying the therapeutic targets involved in pathways associated with the treatment of hair loss and other disorders of skin and hair, including alopecia, skin cancer, skin inflammation, and skin wound healing.

[Scientific Reports] Researchers investigated the role of Hedgehog-GLI signaling in sustaining androgen-independent growth of prostate cancer cells.

[Cell Reports] Scientists found primary medulloblastoma tumors globally displayed decreased expression of GABA transaminase, the protein responsible for GABA metabolism, compared with normal cerebellum.

[Cancer Research] The authors reported that monoamine oxidase A (MAOA), a mitochondrial enzyme that degrades monoamine neurotransmitters and dietary amines, reciprocally interacted with androgen receptor (AR) in prostate cancer.

[Scientific Reports] Scientists established liver tumor cell lines from hepatitis C virus transgenic mice fed an atherogenic high-fat diet.