Tag results:
STAT3
Endothelial Cell News
Membrane Progesterone Receptor α (mPRα) Enhances Hypoxia-Induced Vascular Endothelial Growth Factor Secretion and Angiogenesis in Lung Adenocarcinoma through STAT3 Signaling
[Journal of Translational Medicine] Membrane progesterone receptor α was deregulated within lung adenocarcinoma (LUAD) tissue samples; increased membrane progesterone receptor α contributed to a higher microvessel density in LUAD tissues.
Pancreatic Cell News
Synthetic Adiponectin-Receptor Agonist, AdipoRon, Induces Glycolytic Dependence in Pancreatic Cancer Cells
[Cell Death & Disease] Treatment of PDAC cells with AdipoRon led to mitochondrial uncoupling and loss of ATP production. Concomitantly, AdipoRon-treated cells increased glucose uptake and utilization.
Mammary Cell News
Ultrasound Targeted Microbubble Destruction-Mediated SOCS3 Attenuates Biological Characteristics and Epithelial-Mesenchymal Transition (EMT) of Breast Cancer Stem Cells
[Bioengineered] The authors explored the effects of ultrasound targeted microbubble destruction -mediated transfection of SOCS3 on the biological characteristics and EMT of breast cancer stem cells.
Cancer Stem Cell News
MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation
[Stem Cells International] Researchers explored whether Mesenchymal stem cell- (MSC-) derived extracellular vesicles-delivered lipocalin-type prostaglandin D2 synthase (L-PGDS) could inhibit gastric cancer progression.
Human Immunology News
Modulating Oxidative Stress in B Cells Promotes Immunotherapy in Food Allergy
[Oxidative Medicine and Cellular Longevity] Researchers investigated the role of flagellin in promoting immunotherapy efficacy through modulating oxidative stress in regulatory B cells.
Prostate Cell News
NCAPD3 Promotes Prostate Cancer Progression by Up-Regulating EZH2 and MALAT1 through STAT3 and E2F1
[Cellular Signalling] In vitro and in vivo functional characterization revealed that overexpression of NCAPD3 enhanced the growth of prostate cancer (PCa) cells, while knockdown of NCAPD3 impaired the growth of PCa cells.