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Pancreatic Cell News
Abnormal Cannabidiol Ameliorates Inflammation Preserving Pancreatic Beta Cells in Mouse Models of Experimental Type 1 Diabetes and Beta Cell Damage
[Biomedicine & Pharmacotherapy] Scientists investigated whether Abn-CBD can modulate the inflammatory response during type 1 diabetes (T1D) onset using a mouse model of T1D and of beta cell damage.
Pancreatic Cell News
Eugenosedin-A Improves Obesity-Related Hyperglycemia by Regulating ATP-Sensitive K+ Channels and Insulin Secretion in Pancreatic β Cells
[Biomedicine & Pharmacotherapy] The authors isolated pancreatic islets from adult male Wistar rats and identified pancreatic β-cells by the cell size, capacitance and membrane potential.
Mesenchymal Cell News
Intraperitoneal Administration of Human “Neo-Islets”, 3-D Organoids of Mesenchymal Stromal and Pancreatic Islet Cells, Normalizes Blood Glucose Levels in Streptozotocin-Diabetic NOD/SCID Mice: Significance for...
[PLoS One] A new “endocrine pancreas” delivered islet hormones physiologically into the hepatic portal vein. Treatment of insulin-dependent dogs with allogeneic canine Neo-Islets consistently improved glycemic control without the need for antirejection drugs.
Mesenchymal Cell News
Impact of Insulin Producing Cells Derived from Adipose Tissue Mesenchymal Stem Cells on Testicular Dysfunction of Diabetic Rats
[Heliyon] Scientists investigated the effect of insulin-producing cells derived from adipose tissue MSCs on diabetic-induced impairments as the abnormalities of testicular tissues, oxidative stress of testes, and defects of spermatogenesis.
Cell Therapy News
Deferoxamine Preconditioning Enhances the Protective Effects of Stem Cells in Streptozotocin-Induced Alzheimer’s Disease
[Life Sciences] After induction of the Alzheimer's disease model, the rats were transplanted with deferoxamine-preconditioned adipose-derived mesenchymal stem cells or untreated cells.
Mesenchymal Cell News
Extracellular Vesicles Secreted from Mesenchymal Stem Cells Exert Anti-Apoptotic and Anti-Inflammatory Effects via Transmitting microRNA-18b in Rats with Diabetic Retinopathy
[International Immunopharmacology] Scientists investigated the anti-inflammatory properties of small extracellular vesicles derived from human umbilical cord MSCs in a diabetic rat model and human retinal microvascular endothelial cells.