Sox2

[Biology Open] Activation of activin A signaling stimulated NANOG expression during self-renewal of bovine ESC but suppressed cells expressing pluripotency markers in the blastocyst and increased cells expressing CDX2.

[Stem Cell Research] Researchers employed non-homologous recombination and generated a mouse ESC line carrying a transgene expressing DNMT1 Y495C mutation in the wild-type background as a model for studying the abnormal neurogenesis due to this mutation.

[Cell Death Discovery] The authors found that the stemness characteristics of lung cancer cells were significantly enhanced by the overexpression of non-muscle myosin heavy chain 9 (MYH9), and the knockout of MYH9 had the opposite effects.

[Cellular Oncology] Cell line-derived spheroids, ex vivo intestinal organoid cultures and induced-pluripotent stem cells were used to investigate the role of atypical cyclin P in stemness.

[Stem Cells and Development] To associate the quality of kidney organoid differentiation with predictive markers, a ranking system was developed based on the ratio of nephron structure determined by histological examination.

[Reproductive Toxicology] To explore the developmental toxicity of 2,2',4,4'-Tetrabromodiphenyl ether (BDE47), mouse ESCs, which are ideal models for testing the developmental toxicity of environmental contaminants in vitro, were exposed to BDE47 for 24 h or 48 h in this study.