T cells

[Molecular Therapy Oncolytics] Non-viral/plasmid-based programmed cell death protein 1 (PD-1) knockout was carried out immediately prior to the traditional 14-day tumor-infiltrating lymphocytes-based ACT rapid expansion protocol.

[Science Immunology] Scientists described a population of CXCR5+ T follicular helper–like mucosal-associated invariant T (MAIT) cells that have the capacity to provide B cell help within mucosal lymphoid organs.

[Trends in Immunology] The authors detail the novel cellular sensors that are dependent on K63 ubiquitination for their function in the immune signaling network.

[Cell Reports] Using both wild-type and alpha-synuclein (αS) knockout mice, investigators showed that αS was a critical mediator of inflammatory and immune responses.

[Cell Reports Methods] Scientists showed that fibroblastic, hepatic, or neural tumors were all efficiently infiltrated and partially or totally rejected by autologous immune cells in humanized mice.

[Science Immunology] Investigators applied chromatin conformation capture with immunoprecipitation in Treg and closely related conventional CD4+ T cells.