T cells

[Scandinavian Journal of Rheumatology] Peripheral blood mononuclear cells were obtained from the peripheral blood of healthy individuals and patients with rheumatoid arthritis.

[Cytopathology] Flowcytometry of FNA/ scrape material from 30 cases of benign lymph nodes was evaluated to study the distribution of lymphoid populations and assess presence and percentages of immunophenotypic outliers.

[Journal of Immunology] Using miRNA microarray profiling, investigators characterized the expression profile of naive and in vivo generated murine effector antiviral CD8+ T cells.

[Journal of Immunology Research] Scientists generated a therapeutic chimeric protein containing the PD-L1 single-chain variable fragment linked to a cleavable model cytotoxic T lymphocyte epitope: E7 CTL peptide.

[Nature Medicine] The authors edited the TRAC locus in human peripheral blood T cells to engage cell-surface targets through their T cell receptor–CD3 complex reconfigured to utilize the same immunoglobulin heavy and light chains as a matched CAR.

[International Immunopharmacology] Researchers revealed that nuclear receptor subfamily 4 Group A member 1 was upregulated during cardiac allograft rejection and that the increased Nr4A1 was primarily localized in intragraft-infiltrating CD4+ T cells.