TGF-beta

[Oncogene] Researchers identified a key regulator of macropinocytosis for the survival of tumor cells in a low amino acid environment in pancreatic ductal adenocarcinoma.

[Cell Death & Disease] NR2F1-AS1 and NR2F1 were highly co-expressed in pan-tissues and pan-cancers. Depletion of NR2F1-AS1 compromised the expression level of NR2F1 in gastric cancer cells.

[Scientific Reports] The authors investigated subretinal fibrosis in the laser photocoagulation model of choroidal neovascularization (CNV) by studying the whole transcriptome of the retinal pigment epithelium/choroid following CNV and the application of an anti-fibrotic following CNV.

[Prostate Cancer and Prostatic Diseases] The authors discuss the immunopathology of the prostate tumor microenvironment, strategies for treating prostate cancer with immunotherapies, and a perspective on potential approaches to enhancing the efficacy of immunotherapies.

[Scientific Reports] The importance of MSC miRNAs in modulation of osteoblastic differentiation was examined by global reduction of miRNA biosynthesis in Dicer knock down hMSCs.

[Human Cell] Researchers assessed miR-675-3p-related regulatory mechanisms in melanoma and the clinical relevance of such regulatory activities.