UC-MSCs

[Current Research in Translational Medicine] Researchers investigated the effects of ovine umbilical cord-derived mesenchymal stromal cells seeded in a fibrin patch as an adjuvant therapy for fetal myelomeningocele repair in the ovine model.

[Cell Research] MSC infusion reduced the levels of C-reactive protein, proinflammatory cytokines, and neutrophil extracellular traps, and promoted the maintenance of SARS-CoV-2-specific antibodies.

[Cellular Reprogramming] MSCs were extracted from adipose, umbilical cord, and placental tissues. The expression levels of 80 cytokines were detected, and the data demonstrated that the three MSC types abundantly secreted insulin-like growth factor-binding protein (IGFBP)-4, IGFBP-3, tissue inhibitor of metalloproteinase (TIMP)-1, TIMP-2, IGFBP-6, monocyte chemoattractant protein-1, and granulocyte colony-stimulating factor.

[Stem Cell International] Investigators provide an overview of humab bone-marrow-MSCs, the application of these cells to various neurological diseases, and improvements in their quality and freshness based on integrated omics after detachment from the culture dish for successful cell therapy.

[International Immunopharmacology] To better understand the role of MSC in the prevention and treatment of graft-versus-host disease, umbilical cord derived MSCs were pre-treated with Chinese medicine Asarinin and IFN-γ.

[Human Cell] Researchers aimed to determine whether human umbilical cord-derived-MSCs-exosomes have a hepatoprotective effect on non-alcoholic fatty liver disease.