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UC-MSCs

Comparison of Mesenchymal Stromal Cells from Peritoneal Dialysis Effluent with Those from Umbilical Cords: Characteristics and Therapeutic Effects on Chronic Peritoneal Dialysis in Uremic...

[Stem Cell Research & Therapy] Researchers compared the cytoprotection between peritoneal dialysis (PD) effluent-derived MSCs and umbilical cord-derived MSCs in the treatment of both peritoneal membrane and kidney injury in uremic rats with chronic PD.

Cell Heterogeneity, Rather than the Cell Storage Solution, Affects the Behavior of Mesenchymal Stem Cells In Vitro and In Vivo

[Stem Cell Research & Therapy] Scientists investigated the effects of storage solutions and heterogeneity on the behavior of MSCs in vitro and in vivo.

Human Umbilical Cord-Derived Mesenchymal Stem Cells Improve the Function of Liver in Rats with Acute-on-Chronic Liver Failure via Downregulating Notch and Stat1/Stat3 Signaling

[Stem Cell Research & Therapy] Researchers investigated the therapeutic potential of human umbilical cord-derived MSCs in acute-on-chronic liver injury (ACLI) and ACLF rat models.

Glycemic Control by Umbilical Cord-Derived Mesenchymal Stem Cells Promotes Effects of Fasting-Mimicking Diet on Type 2 Diabetic Mice

[Stem Cell Research & Therapy] The authors investigated the efficacy comparison and interaction between fasting-mimicking diet and umbilical cord-derived-MSC infusion, aiming to establish effective type 2 diabetes therapies and explore its mechanism.

The Tissue Origin of Human Mesenchymal Stem Cells Dictates Their Therapeutic Efficacy on Glucose and Lipid Metabolic Disorders in Type II Diabetic Mice

[Stem Cell Research & Therapy] Scientists report a comprehensive comparison of human MSCs derived from umbilical cord Wharton’s jelly (UC-MSCs), dental pulp, and adipose tissue on the treatment of glucose and lipid metabolic disorders in type II diabetic mice.

Application of Mesenchymal Stem Cell Sheet to Treatment of Ischemic Heart Disease

[Stem Cell Research & Therapy] Umbilical cord (UC)-MSCs have few human leukocyte antigen-II and major histocompatibility complex class I molecules, and are easy to isolate and culture, UC-MSC sheets have been proposed as a candidate for clinical applications to ischemic heart disease.

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