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VGEF

Basic and Therapeutic Aspects of Angiogenesis Updated

[Circulation Research] The authors focus on some recent advances in understanding endothelial cell behavior in health and disease and identify novel molecular players and concepts that could eventually be considered for therapeutic targeting.

Zeb1 Promotes Corneal Neovascularization by Regulation of Vascular Endothelial Cell Proliferation

[Communications Biology] Investigators showed that Zeb1 is an important factor promoting vascular endothelial cell (EC) proliferation and corneal neovascularization (NV); and a couple of small molecule inhibitors can evict Ctbp from the Zeb1–Ctbp complex, thereby reducing EC Zeb1 expression, proliferation, and corneal NV.

Increased Levels of VEGF-C and Macrophage Infiltration in Lipedema Patients without Changes in Lymphatic Vascular Morphology

[Scientific Reports] The histological and molecular characterization was conducted on anatomically-matched skin and fat biopsies as well as serum samples from eleven lipedema and ten BMI-matched healthy patients.

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