acinar cells

[Biochemical Genetics] Investigators explored the role of long-noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) in acute pancreatitis that was induced by caerulein in rat pancreatic acinar cells AR42J.

[Journal of Pathology] Pancreatic ductal metaplasia (PDM) development might involve all cell lineages of the pancreas, and acinar cells with the highest plasticity are the major source of PDM.

[BMC Gastroenterology] Scientists found that palmitic acid stimulation led to M1 polarization of macrophage, which secreted cathepsin S via exosomes to pancreatic acinar cells and led to activation of the caspase1-mediated classical pyrolysis pathway.

[Journal of Pathology] Pancreatic ductal metaplasia (PDM) development might involve all cell lineages of the pancreas, and acinar cells with the highest plasticity are the major source of PDM.

[BMC Gastroenterology] Scientists found that palmitic acid stimulation led to M1 polarization of macrophage, which secreted cathepsin S via exosomes to pancreatic acinar cells and led to activation of the caspase1-mediated classical pyrolysis pathway.

[Molecular Therapy] Scientists showed that microRNA-26a inhibited pancreatic acinar cell store-operated Ca2+ entry channel expression, Ca2+ overload, and acute pancreatitis.