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acute lung injury

Exosomes from Adipose-Derived Mesenchymal Stem Cells Alleviate Sepsis-Induced Lung Injury in Mice by Inhibiting the Secretion of IL-27 in Macrophages

[Cell Death Discovery] The authors investigated the mechanism of exosomes from adipose-derived MSCs in sepsis-induced acute lung injury.

SARS-CoV-2-Triggered Mast Cell Rapid Degranulation Induces Alveolar Epithelial Inflammation and Lung Injury

[Signal Transduction and Targeted Therapy] Scientists showed that SARS-CoV-2-triggered mast cells degranulation initiated alveolar epithelial inflammation and lung injury.

Extracorporeal Membrane Oxygenation in Children Receiving Hematopoietic Cell Transplantation and Immune Effector Cell Therapy: An International and Multidisciplinary Consensus Statement

[Lancet Child & Adolescent Health] The authors provide a clinical decision support tool for pediatric hematologists, oncologists, and critical care physicians during the difficult decision-making process of extracorporeal membrane oxygenation candidacy and management.

ACE2-Like Carboxypeptidase B38-CAP Protects from SARS-CoV-2-Induced Lung Injury

[Nature Communications] Researchers showed that B38-CAP, an ACE2-like enzyme, was protective against SARS-CoV-2-induced lung injury.

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Reduce Lung Inflammation and Damage in Nonclinical Acute Lung Injury: Implications for COVID-19

[PLoS One] Researchers identified a role for MSC-extracellular vesicles in immune modulation and cellular salvage in a model of SARS-CoV-2 induced acute lung injury using pulmonary epithelial cells and exposure to cytokines or the SARS-CoV-2 receptor binding domain.

RvD1 Accelerates the Resolution of Inflammation by Promoting Apoptosis of the Recruited Macrophages via the ALX/FasL-FasR/Caspase-3 Signaling Pathway

[Cell Death Discovery] Mice were administered Resolvin D1 via the tail vein 3 and 4 days after stimulation with lipopolysaccharide.

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