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adipose-derived stem cells

Protective Effects of Low-Molecular-Weight Components of Adipose Stem Cell-Derived Conditioned Medium on Dry Eye Syndrome in Mice

[Scientific Reports] Researchers demonstrated the protective effects of low-molecular-weight adipose-derived stem cell-conditioned medium in a mouse model of dry eye syndrome.

miR-20a Overexpression in Adipose-Derived Mesenchymal Stem Cells Promotes Therapeutic Efficacy in Murine Lupus Nephritis by Regulating Autophagy

[Stem Cells International] Scientists investigated the efficacy of miR-20a overexpressing adipose-derived stem cell transplantation in murine lupus nephritis and explored potential molecular mechanisms.

Insight into the Role of Dermal White Adipose Tissue Loss in Dermal Fibrosis

[Journal of Cellular Physiology] The authors indicate that the adipocytes-to-myofibroblasts transition in dermal white adipose tissue reflects the direct contribution to the dermal fibrosis formation

Adipose-Derived Stem Cells Inhibit Dermal Fibroblast Growth and Induce Apoptosis in Keloids through the Arachidonic Acid-Derived Cyclooxygenase-2/Prostaglandin E2 Cascade by Paracrine

[Burns & Trauma] Scientists found out how the conditioned medium of adipose-derived stem cells exerted an anti-fibrotic effect in keloid dermis-derived fibroblasts.

Adipose-Derived Stem/Stromal Cell Secretome Modulates Breast Cancer Cell Proliferation and Differentiation State towards Aggressiveness

[Biochimie] To understand the role of the adipose-derived stem cell secretome in breast cancer cell proliferation, death, and phenotype alteration, adipose-derived stem cell-conditioned medium was used to cultivate MCF-7 and MDA-MB-231 cells.

Protective Effect of Adipose-Derived Mesenchymal Stem Cell Secretome against Hepatocyte Apoptosis Induced by Liver Ischemia-Reperfusion with Partial Hepatectomy Injury

[Stem Cells International] The authors successfully established laparoscopic liver ischemia-reperfusion with partial hepatectomy in miniature pigs and injected saline, DMEM, adipose-derived stem cell (ADSC)-secretome, and ADSCs directly into the liver parenchyma immediately afterwards.

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