adriamycin

[Laboratory Investigation] Scientists investigated the mechanism by which curcumin affected the resistance of acute myeloid leukemia to Adriamycin by regulating HOX transcript antisense RNA (HOTAIR) expression.

[Experimental and Molecular Medicine] Scientists identified the methyltransferase-like 3/microRNA-221-3p/homeodomain-interacting protein kinase 2/Che-1 (METTL3/miR-221-3p/HIPK2/Che-1) axis as a novel signaling event that may be responsible for resistance of breast cancer cells to adriamycin.

[Nature Communications] Comprehensive data was obtained by a chemical reporter-based method to survey O-GlcNAc function in human breast cancer cells stimulated with the genotoxic agent adriamycin.