asthma

[Journal of Immunology] Scientists showed that PRMT5 drove allergic airway inflammation in a mouse model reproducing multiple aspects of human severe asthma.

[Scientific Reports] Investigators evaluated the anti-inflammatory and antioxidant effects of 18β-GA in an ovalbumin-induced asthma mouse model, and examined the role of NF-κB and Nrf2/HO-1 signaling pathways.

[Cellular and Molecular Life Sciences] Investigators describe the origins, pathogenesis, and clinical features of COVID-19 and the potential uses of MSCs in therapeutic treatments for severe acute respiratory syndrome coronavirus 2-infected patients.

[Seminars in Immunopathology] Innate immune cells contain the molecular circadian clock which drives rhythmic responses, from the magnitude of the inflammatory response to the numbers of circulating immune cells varying throughout the day.

[Respiratory Research] Toll-interacting protein (Tollip) deficient primary human airway epithelial cells from four healthy donors were generated by the gene knockdown approach and stimulated with IL-13 to measure activation of transcription factor STAT3, and eotaxin-3, an eosinophilic chemokine.

[Experimental Physiology] Scientists studied the function of Brahma-related gene-1 (Brg1) in an ovalbumin-induced asthma model and human bronchial epithelial 16HBE cells stably expressing Brg1 shRNA.