astrocytes

[Communications Biology] Linear, adhered rat and human 3D neuronal-astrocyte cultures were developed to enable the study of aggregation and sorting of these cells. An in silico model of the contraction, clustering, and cell sorting in the 3D cultures was also developed.

[PLoS One] To improve treatment of glioblastoma, including those resistant to temozolomide , we explored the potential of targeting dopamine receptor signaling.

[Nature Reviews Neurology] Scientists provide an overview of the diverse roles of non-neuronal cells in relation to the pathogenesis of ALS and the emerging potential of non-neuronal cell biomarkers to advance therapeutic development.

[Proceedings of the National Academy of Sciences of the United States of America] Proteomic changes occurred within five min of intracarotid arterial hyperosmolar mannitol (ICAHM) infusion and returned to baseline by 96 hours. Transcriptomic analyses following ICAHM blood–brain barrier disruption further supported an sterile inflammatory response.

[Advanced Healthcare Materials] Researchers report an in vitro mild traumatic brain injury modeling system based on 3D cultured human iPSC derived neural progenitor cells to evaluate consequences of single and repetitive mild traumatic brain injury using a 3D printed mini weight‐drop impact device.

[Nature Communications] The authors report, the astrocyte-derived secreted lipocalin Glial Lazarillo , a homolog of human Apolipoprotein D, and its neuronal receptor, the brain-specific short isoforms of Drosophila lipophorin receptor 1, cooperatively mediated neuron-glia lipid shuttling and support dendrite morphogenesis.