astrocytes

[Proceedings of the National Academy of Sciences of the United States of America] Genetic lineage tracing and time-course analyses revealed that DLX2 enabled astrocytes to rapidly become ASCL1+ neural progenitor cells, which gave rise to neurons, astrocytes, and oligodendrocytes in the adult mouse striatum.

[Glia] Investigators described an approach to derive microglia from human induced pluripotent stem cells (iPSCs) and integrated them into iPSC-derived midbrain organoids.

[Pathology Research and Practice] Investigators draw an interaction map for glioblastomas (GBMs) and promote awareness of the complexity of the GBM microenvironment.

[Scientific Reports] Nine compounds demonstrated desirable glioblastoma cell toxicity in cell culture, and two of them, HR51, and HR59 demonstrated significantly improved capability of crossing the model blood–brain-barrier composed of endothelial cells, astrocytes and pericytes.

[Frontiers in Cell and Developmental Biology] Beneficial effects were observed with Rapamycin treatment as it decreased the gliotic response and prevented the development of newly formed blood vessels.

[Proceedings of the National Academy of Sciences of the United States of America] Scientists tested whether perinatal intake of a multispecies probiotic could mitigate the abnormal emotional behavior in the juvenile and adult offspring of obese dams.