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breast cancer cells

Cysteine-Rich Domain of Type III Collagen N-Propeptide Inhibits Fibroblast Activation by Attenuating Tgfβ Signaling

[Matrix Biology] Scientists defined type III Collagen as a suppressor of scar formation and desmoplasia through its effects, in part, on myofibroblasts.

Engineering Tumor Constructs to Study Matrix-Dependent Angiogenic Signaling of Breast Cancer Cells

[Biotechnology Progress] Scientists reported the development of an in vitro 3D breast cancer model to investigate the effect of stromal crosslinking and consequent, stiffening on the angiogenic activity of cancer cells.

Label-Free Enrichment of MCF7 Breast Cancer Cells from Leukocytes Using Continuous Flow Dielectrophoresis

[Electrophoresis] Scientists presented a continuous flow, antibody-free dielectrophoresis-based microfluidic device to concentrate MCF7 breast cancer cells, a well-established circulating tumor cells model, in the presence of leukocytes extracted from human blood samples.

In Situ Imaging for Tumor Microbiome Interactions via Imaging Mass Cytometry on Single-Cell Level

[Cytometry Part A] Researchers developed a rapid semi-quantitative method for in situ imaging of bacteria and multiplex cell phenotypes on the same solid tumor tissue sections.

PRMT5 Regulates RNA M6A Demethylation for Doxorubicin Sensitivity in Breast Cancer

[Molecular Therapy] Scientists found that doxorubicin treatment significantly induced RNA m6A methylation in breast cancer cells in both a dose- and time-dependent manner.

YTHDF1 Promotes Breast Cancer Cell Growth, DNA Damage Repair, and Chemoresistance

[Cell Death & Disease] YTHDF1 facilitated S-phase entry, DNA replication and DNA damage repair, and accordingly YTHDF1 knockdown sensitized breast cancer cells to Adriamycin and Cisplatin as well as Olaparib, a PARP inhibitor.

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