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breast cancer stem cells
Mammary Cell News
Lin28B-High Breast Cancer Cells Promote Immune Suppression in the Lung Pre-metastatic Niche via Exosomes and Support Cancer Progression
[Nature Communications] Researchers demonstrated that Lin28B promoted lung metastasis of breast cancer by building an immune-suppressive pre-metastatic niche.
Intestinal Cell News
Fabrication, Characterization and In Vitro Evaluation of Disulfiram-Loaded Cellulose Acetate/Poly(ethylene Oxide) Nanofiber Scaffold for Breast and Colon Cancer Cell Lines Treatment
[International Journal of Biological Macromolecules] Disulfiram (DS)@CA/PEO nanofiber scaffold showed higher safety than DS-free on human normal cells with revealing similar anticancer activity of DS-free against colon cancer line and breast cancer line.
Cancer Stem Cell News
Secretory Phospholipase sPLA2-IIAloss Impairs Tumorigenic and Metastatic Potential in Breast Cancer Cells
[Biochemical and Biophysical Research Communications] Scientists observed an increased level of EMT markers in CSC population. Overexpression of secretory phospholipase sPLA2-IIA was found in CSCs.
Mammary Cell News
Ultrasound Targeted Microbubble Destruction-Mediated SOCS3 Attenuates Biological Characteristics and Epithelial-Mesenchymal Transition (EMT) of Breast Cancer Stem Cells
[Bioengineered] The authors explored the effects of ultrasound targeted microbubble destruction -mediated transfection of SOCS3 on the biological characteristics and EMT of breast cancer stem cells.
Cancer Stem Cell News
Deregulation of the CD44-NANOG-MDR1 Associated Chemoresistance Pathways of Breast Cancer Stem Cells Potentiates the Anti-cancer Effect of Kaempferol in Synergism with Verapamil
[Toxicology and Applied Pharmacology] Researchers used Kaempferol in combination with Verapamil, in multiple assays to determine if there was an inhibitory effect on breast cancer stem cells.
Mammary Cell News
Role, Molecular Mechanism and the Potential Target of Breast Cancer Stem Cells in Breast Cancer Development
[Biomedicine & Pharmacotherapy] Scientists discuss the latest developments in breast cancer stem cells (BCSCs) research, focusing on the analysis of specific markers, critical signaling pathways that maintain the stemness of BCSCs, such as NOTCH, Wnt/β-catenin, STAT3, Hedgehog, and Hippo-YAP signaling.
