breast cancer

[Journal of Steroid Biochemistry and Molecular Biology] The authors investigated the potential interactions of (-)-epicatechin and (+)-catechin with the membrane androgen receptor, ZIP9 (SLC39A9), which mediates androgen induction of apoptosis in human breast and prostate cancer cells.

[Nature Communications] Scientists developed a strategy that enabled single-cell lipidomic analysis with high structural specificity and classified four subtypes of human breast cancer cells.

[Nature Communications] The authors suggested MutL loss as a predictive marker of sensitivity to combinatorial treatment with endocrine intervention and HER inhibitors in endocrine treatment-resistant ER+/HER2− breast cancer patients.

[Oncogene] The authors investigated the contribution of nucleoside diphosphate kinase (NME1), a known metastasis suppressor, to local invasion in breast cancer.

[Oncogene] Scientists investigated the role of Ubiquitin-Specific Protease 22 (USP22) in HER2-driven breast cancer (HER2+-BC) and demonstrated that USP22 was required for the tumorigenic properties in murine and human HER2+-BC models.

[Cell Death & Disease] Investigators studied the interaction between Notch receptors (Notch1-4) and PTEN, and demonstrated that Notch3 inhibited breast cancer proliferation and suppressed tumorigenesis by transactivating PTEN expression.