breast cancer

[Scientific Reports] Researchers analyzed the phytoconstituents in ethanolic Ajwa Dates Pulp Extract by liquid chromatography-mass spectrometry and investigated anticancer effects against MDA-MB-231 cells.

[Cell Death & Disease] The authors examined intracellular levels of let-7f in 4T1 mammary carcinoma cells to test the hypothesis that let-7f released from human mesenchymal stem cells may be incorporated by tumor cells.

[Scientific Reports] Using a model of experimentally induced epithelial-mesenchymal transition (EMT) in human mammary epithelial cells, researchers demonstrated that breast cancer cells enriched for EMT features were more sensitive to cytotoxicity induced by ophiobolin A.

[npj Breast Cancer] The authors summarize currently approved tyrosine kinase inhibitors for HER2+ breast cancer, key clinical trials, and their use in current clinical practice.

[Cell Death Discovery] Scientists explored the impact of macrophage-derived exosomal miR-503-3p in the development of breast cancer by regulating disheveled-associated binding antagonist of beta-catenin 2 (DACT2).

[Cell Death Discovery] Researchers demonstrated that mdivi-1, a putative inhibitor of mitochondrial fission protein Drp1, enhanced the anticancer effects of taxol and overcame taxol resistance in a TNBC cell line.