breast cancer

[Chemmedchem] Tamoxifen (TAM) is a selective estrogen receptor modulator with potential clinical benefits for all stages of breast cancer. Investigators reported novel TAM analogues that could avoid metabolism via CYP2D6.

[Scientific Reports] Investigators used a series of bioinformatics methods and experiments to conduct exploratory research on the possible role of m6A regulators in breast cancer (BC) and revealed that YTHDF1 could serve as a new molecular marker for BC immunotherapy.

[Oncogene] Restoring SELENOF could attenuate a number of aggressive cancer phenotypes in breast cancer cells, including clonogenic survival, and enhance the response to drugs or radiation used in breast cancer therapy.

[Cancer Discovery] Researchers unveiled the ectonucleotide pyrophosphatase /phosphodiesterase 1 (ENPP1)/HP axis as an unanticipated mechanism exploited by tumor cells linking inflammation to immune remodeling favoring local relapse.

[Small] A single therapeutic was developed based on trastuzumab-conjugated nanoparticles for co-delivering docetaxel and siRNA against HER2.

[Archives of Gynecology and Obstetrics] Researchers investigated the nuclear peroxisome proliferator-activated receptor gamma-dependent proliferation behavior of breast cancer cells after stimulation with matcha green tea extract.