Tag results:

breast cancer

BriaCell Advances Preparatory Work for New Bria-OTS™ Breast Cancer Clinical Trial

[BriaCell Therapeutics Corp.] BriaCell Therapeutics Corp., announced that its novel off-the-shelf (OTS) personalized immunotherapy, Bria-OTS™, is currently being manufactured at a cGMP facility and undergoing quality control testing for the potential upcoming clinical trial for patients with advanced breast cancer.

IBA and UMC Groningen Engage in FLASH Irradiation Research Collaboration for Breast Cancer

[Ion Beam Applications S.A.] Ion Beam Applications S.A. (IBA), and the University Medical Center Groningen (UMCG) announced a four-year research collaboration agreement towards development of a new FLASH irradiation protocol for the treatment of early-stage breast cancer.

Modification of BRCA1-Associated Breast Cancer Risk by HMMR Overexpression

[Nature Communications] Researchers depicted an interplay of molecular, cellular, and tissue microenvironment alterations that increased BRCA1-associated breast cancer risk.

The Natural Antisense Transcript HAS2-AS1 Regulates Breast Cancer Cells Aggressiveness Independently from Hyaluronan Metabolism

[Matrix Biology] Scientists reported that estrogen receptor (ER)-positive breast cancers had lower hyaluronan synthase 2 antisense RNA 1 (HAS2-AS1) expression compared to ER-negative tumors. Moreover, the survival of patients with ER-negative tumors was higher when the expression of HAS2-AS1 was elevated.

FER Regulates Endosomal Recycling and Is a Predictor for Adjuvant Taxane Benefit in Breast Cancer

[Cell Reports] The authors showed that high feline sarcoma-related non-receptor tyrosine kinase (FER) levels were also associated with improved outcomes after adjuvant taxane-based combination chemotherapy in high-risk, HER2-negative patients.

HspBP1 Is a Dual Function Regulatory Protein That Controls Both DNA Repair and Apoptosis in Breast Cancer Cells

[Cell Death & Disease] Investigators showed that when Hsp70-binding protein 1 (HspBP1) was either knocked down or overexpressed in BRCA1-proficient breast cancer cells, there were profound changes in tumorigenesis, including anchorage-independent cell growth in vitro and in tumor formation in xenograft models.