breast cancer

[Cell Death & Disease] The authors used the breast cancer mouse model MMTV-PyMT, and constructed a single-cell atlas of 31,778 cells from four distinct stages of tumor progression, during which malignant transition occured.

[Life Sciences] Scientists reported that IFN-γ and insulin possessed pro-proliferative effects in breast cancer and non-cancer cell lines, respectively, which were dependent on increased ASCT2-mediated glutamine transport.

[Journal of Cellular and Molecular Medicine] Scientists illustrated and summarized the correlations between endocrine therapy resistance in breast cancer and prolactin (PRL), as well as the pathophysiological mechanisms and clinical practices.

[International Journal of Health Geographics] Investigators perform a systematic review of epidemiological evidence on the association between LAN exposure and breast cancer risk, using a dose–response meta-analysis and examining the shape of the relation.

[Menarini Group] The Menarini Group and Radius Health, Inc. announced positive topline results from the EMERALD study evaluating elacestrant as a monotherapy versus the standard of care for the treatment of ER+/HER2- advanced or metastatic breast cancer.

[FEBS Journal] Scientists reported on the epidermal growth factor receptor (EGFR)-estrogen receptor beta (ERβ) functional relationship in connection to the aggressiveness and cancer stem cell-like characteristics of triple-negative breast cancer cells.