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breast cancer

Interleukin-30 Feeds Breast Cancer Stem Cells via CXCL10 and IL23 Autocrine Loops and Shapes Immune Contexture and Host Outcome

[Journal For Immunotherapy of Cancer] Human and murine breast CSCs were tested for their production of and response to IL30 by using flow cytometry, confocal microscopy, proliferation and sphere-formation assays, and PCR array.

The Membrane-Linked Adaptor FRS2β Fashions a Cytokine-Rich Inflammatory Microenvironment That Promotes Breast Cancer Carcinogenesis

[Proceedings of the National Academy of Sciences of the United States of America] Researchers demonstrated that FRS2β, an adaptor protein expressed in a small subset of epithelial cells, triggered the proinflammatory changes that induced stroma in premalignant mammary tissues and was responsible for the disease onset.

Cell Viability and Electrical Response of Breast Cancer Cell Treated in Aqueous Graphene Oxide Solution Deposition on Interdigitated Electrode

[Scientific Reports] Scientists investigated the cell viability and electrical response of graphene oxide (GO), in terms of resistivity and impedance towards the breast cancer cells and normal breast cells, by varying the pH and concentration of GO.

DGUOK-AS1 Acts as a Tumor Promoter through Regulating miR-204-5p/IL11 Axis in Breast Cancer

[Molecular Therapy-Nucleic Acids] The authors reported DGUOK-AS1 overexpression promoted breast cancer cell migration, angiogenesis, and macrophage migration, mediated by the increased secretion of IL11, which was extremely important for cancer progression.

CircGFRA1 Facilitates the Malignant Progression of HER-2-Positive Breast Cancer via Acting as a Sponge of miR-1228 and Enhancing AIFM2 Expression

[Journal of Cellular and Molecular Medicine] Researchers employed various in vitro along with in vivo assays and explored the effects of circGFRA1 in the progress of HER-2-positive breast cancer (BC) and interactions of circGFRA1, miR-1228 and AIFM2 in HER-2-positive BC.

Expression and Functions of Long Non-coding RNA NEAT1 and Isoforms in Breast Cancer

[British Journal of Cancer] The authors review the current knowledge of NEAT1 expression and functions in breast cancer, highlighting its established role in postnatal mammary gland development.

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