bronchial epithelial cells

[Oncogene] Scientists explored the mechanisms regulating histone methylation in lung adenocarcinoma (LUAD) in response to smoking. They found that the histone H3K9 methylation reader CBX3 was upregulated in current smokers with LUAD, and that CBX3 overexpression promoted LUAD progression.

[Pulmonary Pharmacology & Therapeutics] Researchers investigated the effects of PCI-34051-induced human bronchial epithelial cells-derived exosomes on human bronchial smooth muscle cells and the key exosomal miRNAs involved in this process.

[Cell Biochemistry and Biophysics] Researchers investigated the role of lysocardiolipin acyltransferase expression and activity in mitochondrial oxidative stress, mitochondrial dynamics, and lung epithelial cell apoptosis.

[Pediatric Pulmonology] Human bronchial epithelial cells BEAS-2B were stimulated with transforming growth factor-β1 at a concentration of 10 ng/mL, and CCCTC-binding factor (CTCF) overexpression plasmid and CTCF small interfering RNA were transfected into the cells.

[American Journal of Physiology-Cell Physiology] Researchers investigated how culture of normal human bronchial epithelial cells with apically applied secretions from healthy or disease lungs affected epithelial function with a view to providing better in vitro models of the in vivo environment.

[Scientific Reports] Scientists tested whether sphingosine has any adverse effects in the respiratory tract when applied into isolated ventilated and perfused lungs. A four hour ex vivo lung perfusion run using minipig lungs was performed.