CU06-1004 Enhances Vascular Integrity and Improves Cardiac Remodeling by Suppressing Edema and Inflammation in Myocardial Ischemia–Reperfusion Injury

Investigators found that CU06-1004, as a vascular leakage blocker, could improve cardiac function by inhibiting cardiac microvascular endothelial cells’ hyperpermeability and subsequently reducing the neutrophil’s plugging and infiltration in infarcted hearts.
[Experimental and Molecular Medicine]
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Cardiac Telocytes Inhibit Cardiac Microvascular Endothelial Cell Apoptosis through Exosomal miRNA-21-5p-Targeted cdip1 Silencing to Improve Angiogenesis following Myocardial Infarction

Investigators showed that cardiac telocytes (CTs) inhibited cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cell death inducing p53 target 1 silencing to improve angiogenesis in myocardial infarction.
[Theranostics]
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