caspase-3

[Cancer Cell International] Long non-coding RNAs and miRs are differentially expressed in ovarian cancer (OC) cells and influence OC progression. Investigators explored the underlying roles of LINC00115 and miR-30a in OC.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers reported that ventrolateral medulla (VLM) catecholaminergic neurons in the mouse brain were activated in tumor-bearing mice and the activity of these neurons significantly altered tumor growth in multiple syngeneic and spontaneous mouse tumor models.

[Molecular Metabolism] Researchers introduced SNAPf-tag into the N-terminal segment of GPR56 to enable monitoring of GPR56 cellular activity in situ.

[Journal of Molecular Endocrinology] Researchers investigated the mechanism of dexamethasone-induced pancreatic β-cell apoptosis through the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) pathway in cultured cells and isolated mouse islets.

[Clinical Cancer Research] Patient tumor organoids (PTO) were fabricated using unsorted tumor cells with and without enrichment with patient matched immune components derived from peripheral blood leukocytes, spleen, or lymph nodes.

[Chemico-Biological interactions] The effects of prodrug 1 were studied in lipopolysaccharide-induced in vitro and in vivo apoptosis and pancreatitis models by determining the cellular apoptotic levels with human umbilical vein endothelial cells and pancreatic caspase-3/-7 activity in mice.