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Adiponectin Triggers Breast Cancer Cell Death via Fatty Acid Metabolic Reprogramming

[Journal of Experimental & Clinical Cancer Research] The authors elucidated the multifaceted role of adiponectin in tumor fatty acid metabolic reprogramming and provided evidence for the connection between its metabolic actions and suppression of breast cancer.

Enhanced Apoptosis as a Possible Mechanism to Self-Limit SARS-CoV-2 Replication in Porcine Primary Respiratory Epithelial Cells in Contrast to Human Cells

[Cell Death Discovery] Researchers investigated species-specific cell susceptibility, virus dose-dependent infectivity, and infection kinetics, using primary human and porcine respiratory epithelial cells.

Tenofovir Disoproxil Fumarate Directly Ameliorates Liver Fibrosis by Inducing Hepatic Stellate Cell Apoptosis via Downregulation of PI3K/Akt/mTOR Signaling Pathway

[PLoS One] Activated hepatic stellate cell cell lines were used to evaluate the effects of tenofovir disoproxil fumarate and entecavir. After treatment with each antiviral agent, cell viability, morphology, apoptotic features, autophagy and antifibrosis signaling pathways were examined.

AIFM1, Negatively Regulated by miR-145-5p, Aggravates Hypoxia-Induced Cardiomyocyte Injury

[Biomedical Journal] Scientists probed into the role and the underlying regulatory mechanism of apoptosis-inducing factor mitochondria associated 1 (AIFM1) in myocardial injury.

Berberine Increases the Expression of Cytokines and Proteins Linked to Apoptosis in Human Melanoma Cells

[Molecular Biology Reports] Researchers reported that berberine has important antiproliferative effects and may be alone or in adjunct therapy a promising candidate for melanoma treatment, a cancer with great incidence and high lethality.

Anti-Breast Cancer Synthetic Peptides Derived from the Anabas testudineus Skin Mucus Fractions

[Scientific Reports] The authors characterized the anticancer activity of the A. testudineus antimicrobial peptides, which were synthetically produced and subjected to cytotoxic assay to prove their efficacy against cancer cell lines.

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