cell culture

[Journal of Cellular and Molecular Medicine] High serum CD44 levels may help identify docetaxel-resistant patients and may thereby help optimize clinical decision-making regarding type and timing of therapy for metastatic CRPC patients patients.

[Annual Review of Neuroscience] Organoids hold promise for the study of atypical cellular, molecular, and genetic features that underscore neurological diseases.

[Translational Oncology] Researchers developed a new PAK4 inhibitor, PAKib and tested its effect on pancreatic cancer (PC) cell growth in vitro and in a syngeneic mouse model of PC.

[Adipocyte] The authors provided in vivo evidence that lysosomal acid lipase-deficiency impaired proliferation of endothelial cells in thermogenic adipose tissue.

[Heliyon] Researchers suggested that galactosylated nanoliposomes incorporating ARV-825 was a novel actively targeted PROTAC-based nanotherapeutic approach for hepatocellular carcinoma.

[Nature Communications] Scientists provided evidence that embryo-like structures can be generated solely based on transcription factor-mediated reprogramming of embryonic stem cells in a simple 3D co-culture system.