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cell proliferation

Egr-1 Inhibits Colon Cancer Cell Proliferation, Migration and Invasion via Regulating CDKL1 at the Transcriptional Level

[Oncology Reports] Overexpression of Egr‑1 inhibited colon cancer cell proliferation, migration, and invasion, whereas knockdown of Egr‑1 increased colon cancer cell proliferation, migration and invasion.

Tumor-Associated Hematopoietic Stem and Progenitor Cells Positively Linked to Glioblastoma Progression

[Nature Communications] Researchers identified and validated the presence of hematopoietic stem and progenitor cells (HSPCs) within glioblastoma tissues, and demonstrated a positive link of tumor-associated HSPCs with malignant and immunosuppressive phenotypes.

Tumor-Associated Hematopoietic Stem and Progenitor Cells Positively Linked to Glioblastoma Progression

[Nature Communications] Scientists identified and validated the presence of hematopoietic stem and progenitor cells within glioblastoma tissues.

Mesenchymal Stem Cells in Glioblastoma Therapy and Progression: How One Cell Does It All

[Biochimica Et Biophysica Acta-Reviews On Cancer] Investigators elaborate on all mentioned contradictory data and provides a realistic, current clinical perspective on MSCs' potential in glioblastoma treatment.

Pharmacoepigenomics Circuits Induced by a Novel Retinoid-Polyamine Conjugate in Human Immortalized Keratinocytes

[Pharmacogenomics Journal] Scientists treated HaCaT cells which resembled human epidermis with IC50 concentration of all-trans-Retinoic Acid-spermine conjugate and analyzed their miRNA expression profile.

PCGF1 Promotes Epigenetic Activation of Stemness Markers and Colorectal Cancer Stem Cell Enrichment

[Cell Death & Disease] Investigators identified PCGF1 as a crucial epigenetic regulator that sustained the stem cell-like phenotype of colorectal cancer (CRC). PCGF1 knockdown inhibited CRC stem cell proliferation and CRC stem cell enrichment.

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