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cell proliferation

Alternative Medicine: Therapeutic Effects on Gastric Original Signet Ring Carcinoma via Ascorbate and Combination with Sodium Alpha Lipoate

[BMC Complementary and Alternative Medicine] Two natural supplements, ascorbate and sodium alpha lipoate, in a series of combinations were incubated with non-signet ring cell carcinoma (SRCC) cells, patient-derived gastric origin SRCC, gastric-origin SRCCs, human pancreatic and ovarian cells for evaluating their therapeutic effects.

Synergetic Integrations of Bone Marrow Stem Cells and Transforming Growth Factor-β1 Loaded Chitosan Nanoparticles Blended Silk Fibroin Injectable Hydrogel to Enhance Repair and Regeneration...

[International Wound Journal] Scientists developed a TGF-β1-silk fibroin blended with polylysine modified chitosan polymer injectable hydrogel that demonstrated enhanced in vitro and in vivo tissue regeneration properties, which led to efficacious therapeutic potential in cartilage regeneration.

Long Noncoding RNA LINC00518 Contributes to Proliferation and Metastasis in Lung Adenocarcinoma via the miR-335-3p/CTHRC1 Axis

[Cell Death Discovery] Investigators verified that the cell proliferation, colony formation, migration, and invasion of lung adenocarcinoma could be inhibited by the knockdown of long intergenic nonprotein coding RNA 518 (LINC00518).

Rab8A Promotes Breast Cancer Progression by Increasing Surface Expression of Tropomyosin-Related Kinase B

[Cancer Letters] Researchers investigated the interaction of ras-related protein in brain (Rab8A) and tropomyosin-related kinase B in regulating the progression of breast cancer. Rab8A was upregulated in breast cancer tissues.

Loss of IRF7 Accelerates Acute Myeloid Leukemia Progression and Induces VCAM1-VLA-4 Mediated Intracerebral Invasion

[Oncogene] The authors used MLL-AF9-induced AML mouse models with interferon regulatory factor 7 (IRF7) knockout or overexpression and xenograft mouse models to explore the intrinsic effects of IRF7 in AML.

Rapid Synchronous Type 1 IFN and Virus-Specific T Cell Responses Characterize First Wave Non-severe SARS-CoV-2 Infections

[Cell Reports Medicine] The authors used blood transcriptomics, multiparameter flow cytometry, and T cell receptor sequencing spanning the time of incident non-severe infection in unvaccinated virus-naive individuals to identify rapid type 1 interferon (IFN) responses common to other acute respiratory viruses and cell proliferation responses that discriminate SARS-CoV-2 from other viruses.

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