cell proliferation

[Scientific Reports] Scientists established a novel method to generate CSCs from iPSCs under a cancerous microenvironment mimicked by the conditioned medium of cancer-derived cells.

[Scientific Reports] Investigators assessed the anti-cancer effects of hibernating common carp plasma on 4T1 cancer cells in vitro and in vivo.

[Heliyon] Various tissue expression profiles of miRNAs using three microarray datasets from groups in Asia, Europe, America and multiple bioinformatics tools were integrated to determine the most significant miRNA groups to assist in the diagnosis of HCC.

[European Journal of Pharmacology] The authors discuss how aberrant expression of C-X-C motif chemokine 12 (CXCL12)/C-X-C chemokine receptor type 4 (CXCR4) and CXCL12/CXCR7 pathways might regulate leukemogenesis and end by outlining the key news of preclinical and clinical investigations in leukemia treatment.

[Endocrine Journal] Human umbilical cord mesenchymal stem cells treatment significantly alleviated inflammation, reduced serum thyroid antibody levels, and decreased the ratios of IL-17α+/CD25+FOXP3+ cells and serum IFN-γ/IL-4 in experimental autoimmune thyroiditis rats.

[Oncogene] Scientists demonstrated that oncogenic LINC021 specifically bound with the m6A “reader” IMP2 protein and enhanced the mRNA stability of MSX1 and JARID2 in an m6A regulatory manner during CRC tumorigenesis and pathogenesis.