cell proliferation

[iScience] Scientists combined single-cell transcriptomic, proteomic, and chromatin accessibility data to investigate how heterogeneous phenotypes contributed to metastatic potential in five HCC cell lines.

[Scientific Reports] Using in silico and in vitro techniques, investigators demonstrated heterogeneous expression of CD97, a leukocyte adhesion marker, in human glioblastoma.

[Proceedings of the National Academy of Sciences of the United States of America] Scientists developed a clinically translatable approach for labeling CAR T cells with iron oxide nanoparticles, which enabled the noninvasive detection of the iron-labeled T cells with magnetic resonance imaging, photoacoustic imaging, and magnetic particle imaging.

[Cancer Gene Therapy] Cyclin-dependent kinase 12 (CDK12) activated MYC to repress miR-28-5p/EZH2 and amplified tonic BCR signaling to promote the development of diffuse large B cell lymphoma (DLBCL), which might provide potential therapeutic targets for future therapeutic intervention in DLBCL.

[Chemico-Biological interactions] Researchers found that benzene exposure significantly increased Evi1 level in white blood cells in occupational benzene workers as well as mouse bone marrow cells.

[Cell Communication and Signaling] The biological role of copine 1 (CPNE1) and receptor for activated C kinase 1 (RACK1) in NSCLC was investigated using gene expression knockdown and overexpression, cell proliferation assays, clonogenic assays, and Transwell assays.