cell proliferation

[Scientific Reports] Researchers showed that increasing NTF2 expression in WM983B metastatic melanoma cells reduced cell proliferation and motility while increasing apoptosis. They also demonstrated that increasing NTF2 expression in these cells significantly inhibited metastasis and prolonged survival of mice.

[Bioengineered] Researchers clarified the role of hydroxysafflor yellow A in inhibiting colorectal cancer in vitro and the underlying mechanisms.

[Journal of Surgical Oncology] The authors explored the expression level of miR-214-5p in prostate cancer and made a preliminary study of its molecular mechanism in the development of prostate cancer to provide effective new strategies for the treatment of prostate cancer.

[andrology] CCK-8, colony formation, transwell, tube formation and flow cytometry assays were applied to assess cell proliferation, motility, angiogenesis, cell cycle distribution and apoptosis.

[Molecular Pharmacology] Elevated expression of lysine demethylase 6A (KDM6A) and 6B (KDM6B) has been reported in prostate cancer (PCa). Scientists reported novel KDM6A/B downstream targets involved in controlling PCa cell proliferation.

[Prostate] The authors investigated a combination therapy of novel androgen receptor (AR) antagonists and statin, simvastatin, for CRPC and found that a combination of novel AR antagonists and simvastatin could potentially affect CRPC growth through both androgen-dependent and androgen-independent mechanisms.