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cell proliferation

A MYBL2 Complex for RRM2 Transactivation and the Synthetic Effect of MYBL2 Knockdown with WEE1 Inhibition against Colorectal Cancer

[Cell Death & Disease] Ectopic expression and knockdown experiments indicated that MYBL2 was essential for colorectal cell proliferation, DNA synthesis, and cell cycle progression in an ribonucleotide reductase small subunit M2 (RRM2)-dependent manner.

Histone Methyltransferase SETD1A Participates in Lung Cancer Progression

[Thoracic Cancer] Researchers found that the SET domain containing 1A (SETD1A), the enzyme for methylation of histone 3 lysine 4, was elevated in lung cancer tissue compared to normal lung tissue.

Implication of Human Endogenous Retrovirus W Family Envelope in Hepatocellular Carcinoma Promotes MEK/ERK-Mediated Metastatic Invasiveness and Doxorubicin Resistance

[Cell Death Discovery] There is no report on the expression pattern and potential mechanism of Syncytin-1 in hepatocellular carcinoma (HCC). Functional experiments in vitro and in vivo demonstrated that Syncytin-1 enhanced cell proliferation, metastasis, and tumorigenicity in HCC.

Resveratrol Promotes Skin Wound Healing by Regulating the miR-212/CASP8 Axis

[Laboratory Investigation] Resveratrol (RES) may have potential as a therapy for wound healing, but how and whether RES regulates skin repair remains poorly understood. Human epidermal keratinocyte cells were treated with lipopolysaccharide, and a mouse skin wound-healing model was established.

Exosomes Secreted by Palmitic Acid-Treated Hepatocytes Promote LX-2 Cell Activation by Transferring miRNA-107

[Cell Death Discovery] Scientists explored the role of exosomes derived from palmitic acid -treated hepatocytes in regulating hepatic stellate cells (LX-2 cell) proliferation and activation and the underlying mechanisms.

Bioengineered 3D Nanocomposite Based on Gold Nanoparticles and Gelatin Nanofibers for Bone Regeneration: In Vitro and In Vivo Study

[Scientific Reports] Scientists fabricated 3D scaffold based on poly (L-lactic acid)/Polycaprolactone matrix polymer containing gelatin nanofibers and gold nanoparticles as the scaffold for bone tissue engineering application.

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