Tag results:
cell proliferation
Dermal Cell News
LncRNA MSC-AS1 Motivates the Development of Melanoma by Binding to miR-302a-3p and Recruiting IGF2BP2 to Elevate LEF1 Expression
[Experimental Dermatology] The silencing of long non-coding RNAs (lncRNA) MSC antisense RNA 1 (MSC-AS1) hindered cell proliferation, migration and epithelial-mesenchymal transition in vitro and tumor growth
Prostate Cell News
High Expression of miR-17-5p in Tumor Epithelium Is a Predictor for Poor Prognosis for Prostate Cancer Patients
[Scientific Reports] In vitro analyses confirmed association between overexpression of miR-17-5p and proliferation, migration and invasion in prostate cancer cell lines.
Extracellular Matrix News
Dual Effects of Atorvastatin on Angiogenesis Pathways in the Differentiation of Mesenchymal Stem Cells
[European Journal of Pharmacology] Researchers studied atorvastatin effects on the angiogenesis-signaling pathways from MSCs' differentiation to tissue angiogenesis.
Prostate Cell News
A Kinome-Centered CRISPR-Cas9 Screen Identifies Activated BRAF to Modulate Enzalutamide Resistance with Potential Therapeutic Implications in BRAF-Mutated Prostate Cancer
[Scientific Reports] Through a kinome-centered CRISPR-Cas9 screen in CWR-R1 prostate cancer cells, scientists identified activated BRAF signaling as a determinant for enzalutamide resistance.
Mesenchymal Cell News
HMGB2 Orchestrates Mitotic Clonal Expansion by Binding to the Promoter of C/EBPβ to Facilitate Adipogenesis
[Cell Death & Disease] Researchers provided evidence that high-mobility group box 2 (HMGB2) deficiency in preadipocytes impeded adipogenesis, while overexpression of HMGB2 increased the potential for adipogenic differentiation.
Intestinal Cell News
Microenvironmental Innate Immune Signaling and Cell Mechanical Responses Promote Tumor Growth
[Developmental Cell] Using a Drosophila intestinal model, scientists found that tumor cells outcompeted nearby enterocytes by influencing cell adhesion and contractility.