Tag results:
cell transplantation
Hematopoiesis News
Jasper Therapeutics Initiates New Clinical Trial with National Cancer Institute to Evaluate JSP191 in GATA2-Related Myelodysplastic Syndromes
[Jasper Therapeutics, Inc. (Business Wire, Inc.)] Jasper Therapeutics, Inc. announced the initiation of a Phase I/II clinical trial to evaluate JSP191, the company’s anti-CD117 monoclonal antibody, as a targeted, non-toxic conditioning agent prior to allogeneic transplant in patients with GATA2-related myelodysplastic syndromes.
Umbilical & Placental Cell News
Significance of Regional Population HLA Immunogenetic Datasets in the Efficacy of Umbilical Cord Blood Banks and Marrow Donor Registries: A Study of Cretan HLA...
[Cytotherapy] Researchers highlighted the importance of regional public cord blood banks in fulfilling hematopoietic stem cell transplantation needs, especially in countries with significant genetic diversity.
Umbilical & Placental Cell News
Comparison of Haploidentical and Umbilical Cord Blood Transplantation after Myeloablative Conditioning
[Blood Advances] Researchers evaluated outcomes in patients with hematological malignancy treated with myeloablative conditioning prior to haplo or umbilical cord blood hematopoietic stem cell transplantation.
Intestinal Cell News
The Scaffold-Dependent Function of RIPK1 in Dendritic Cells Promotes Injury-Induced Colitis
[Mucosal Immunology] Researchers generated dendritic cell-specific Ripk1−/− mice in a genetic background with loss of RIPK1 kinase activity and found that the mice developed spontaneous colonic inflammation characterized by increased neutrophil and Ly6C+ monocytes.
Hematopoiesis News
Novel CAR T Therapy Is a Ray of Hope in the Treatment of Seriously Ill AML Patients
[Stem Cell Research & Therapy] Scientists discuss and explain the most recent advances in chimeric antigen receptor (CAR) T cell-based therapies targeting acute myeloid leukemia (AML) antigens and review the results of preclinical and clinical trials.
Cell Therapy News
Putting Function Back in Dysfunction: Endothelial Diseases and Current Therapies in Hematopoietic Stem Cell Transplantation and Cellular Therapies
[Blood Reviews] Scientists summarize the current knowledge about statins and other agents used as endothelial protectants. They propose further studies using statins for prophylaxis and prevention of end-organ damage related to extensive endothelial dysfunction in hematopoietic stem cell transplantation and chimeric antigen receptor-T cells.