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cell transplantation

Cryopreservation of Unrelated Donor Hematopoietic Stem Cells: The Right Answer for Transplantations during the COVID-19 Pandemic?

[Bone Marrow Transplantation] Investigators compared 32 patients who underwent unrelated donor (UD) hematopoietic stem cell transplantation (HSCT) using cryopreserved peripheral blood stem cells (PBSC) during the COVID-19 pandemic with 32 patients who underwent UD HSCT using fresh PBSC in the previous period.

60 Years Young: The Evolving Role of Allogeneic Hematopoietic Stem Cell Transplantation in Cancer Immunotherapy

[Cancer Research] The authors review the historical basis underpinning the development of allogeneic hematopoietic stem cell transplantation (allo-HSCT) as well as advances in knowledge obtained by defining mechanisms of allo-HSCT activity.

Human Endometrium-Derived Stem Cell Improves Cardiac Function after Myocardial Ischemic Injury by Enhancing Angiogenesis and Myocardial Metabolism

[Current Stem Cell Research & Therapy] Investigators investigated whether human endometrium-derived stem cells could be used for cardiac repair after ischemic injury and their possible underlying mechanisms.

BlueRock Therapeutics Announces First Patient Dosed with DA01 in Phase I Study in Patients with Advanced Parkinson’s Disease

[BlueRock Therapeutics] BlueRock Therapeutics announced the dose administration for the first patient in a Phase I, open-label study of PSC-derived dopaminergic neurons in patients with advanced Parkinson’s disease.

Emerging Understanding of Apoptosis in Mediating Mesenchymal Stem Cell Therapy

[Cell Death & Disease] Investigators summarize the emerging understanding of apoptosis in mediating mesenchymal stem cell transplant, highlighting the potential of apoptotic extracellular vesicles as cell-free therapeutics.

Prognostic Value of Measurable Residual Disease Monitoring by Next-Generation Sequencing before and after Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia

[Blood Cancer Journal] The authors collected samples before and after allogeneic hematopoietic stem cell transplantation from two independent prospective cohorts and investigated the prognostic impact of amplicon-based next-generation sequencing-based assessment.

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